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The dynamics of the acute ischemic stroke (AIS) market are anticipated to change during the forecast period (2023–2032) owing to the improved knowledge of stroke pathophysiology, awareness of symptoms, and developments in acute stroke care in the last two decades, which are increasing the demand for better diagnosis and treatment options for acute ischemic stroke.
LAS VEGAS, May 9, 2023 /PRNewswire/ -- DelveInsight's Acute Ischemic Stroke Market Insights report includes a comprehensive understanding of current treatment practices, acute ischemic stroke emerging drugs, market share of individual therapies, and current and forecasted market size from 2019 to 2032, segmented into 7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan].
Key Takeaways from the Acute Ischemic Stroke Market Report
Discover which therapies are expected to grab the major acute ischemic stroke market share @ Acute Ischemic Stroke Market Report
Acute Ischemic Stroke Overview
According to the Centers for Disease Control and Prevention (CDC), a stroke occurs when a blood artery that provides oxygen and nutrients to the brain becomes clogged by a clot or bursts. Brain cells die when they are deprived of the necessary blood. Acute ischemic stroke symptoms vary according to the intensity and location of the stroke in the brain. Acute ischemic stroke is characterized by sudden onset numbness or weakness in an arm or leg, facial droop, difficulties speaking or comprehending speech, disorientation, balance or coordination problems, and loss of vision. Stroke severity can be classified using NIHSS scores: extremely severe: >25; severe: 15-24; mild to moderately severe: 5-14; mild: 1-5. Acute ischemic stroke is diagnosed mainly by history and physical examination. Key characteristics to consider include difficulties speaking, specific neurological impairments, and an altered degree of consciousness.
Acute Ischemic Stroke Epidemiology Segmentation
DelveInsight estimates that there were approximately 1.6 million diagnosed incident cases of acute ischemic stroke in the 7MM in 2022.
As per DelveInsight's epidemiology model, acute ischemic stroke is seen more among males than in females in the 7MM. However, in the US, more females are affected by AIS than males.
The acute ischemic stroke market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:
Acute Ischemic Stroke Treatment Market
Currently, the medical approach to acute ischemic stroke treatment focuses on treating the acute phase to slow the progression of the ischemia, followed by an effort at revascularization and reperfusion of the brain parenchyma. Further acute ischemic stroke treatment includes minimizing the ischemia-induced damage, neuronal cell death, and the ensuing metabolic cascade generated by the sudden reperfusion. This includes neuroprotective techniques as well as a pharmaceutical approach to lowering inflammation. Finally, acute ischemic stroke treatment focuses on rehabilitation, slowing the progression of vascular disease, and preventing future strokes.
Currently, just one medicine, alteplase, is approved, and around 70% of people are ineligible for the therapy. Furthermore, EVT, a mechanical thrombectomy for clot removal, is approved but only for patients with major artery blockage. Despite these groundbreaking developments, there is still a significant unmet need among NIHSS 6 score patients and patients who are ineligible for IV tPA and EVT due to time constraints and other factors. Furthermore, the stroke burden has not decreased considerably; one reason for this tendency could be the increasing number of individuals with stroke risk factors such as diabetes, hypertension, and hyperlipidemia. Nonetheless, the present pipeline includes promising medicines with a larger administration window that suits the demands of ineligible individuals.
To know more about acute ischemic stroke treatment guidelines, visit @ Acute Ischemic Stroke Management
Acute Ischemic Stroke Therapies and Key Companies
Learn more about the FDA-approved drugs for acute ischemic stroke @ Drugs for Acute Ischemic Stroke Treatment
Acute Ischemic Stroke Market Dynamics
The acute ischemic stroke market is expected to show positive growth in the coming years due to factors such as improved knowledge of stroke pathophysiology, awareness of symptoms, and developments in acute stroke care in the last two decades. Aside from acute ischemic stroke therapy for individuals who are ineligible for tPA or mechanical thrombectomy, certain therapies for secondary prevention of non-cardioembolic ischemic stroke are being developed. Asundexian (Bayer) and milvexian (Bristol Myers Squibb) are two examples. Furthermore, glenzocimab and 3K3A-APC are being developed as supplements to the existing course of care. Moreover, the future of the acute ischemic stroke market offers tremendous potential, with a robust acute ischemic stroke pipeline attempting to target the underserved acute ischemic stroke market. Furthermore, various organizations actively strive to disseminate information and raise awareness about such disorders. As there are fewer acute ischemic stroke therapy choices, the acute ischemic stroke market will grow in the coming years.
However, several factors are impeding the growth of the acute ischemic stroke market. EVT therapy is only available to a subset of acute ischemic stroke patients with major vascular blockage. Most AIS patients are ineligible for treatment because IV rtPA therapy only has 3-4 hours of the therapeutic window. Furthermore, stroke assessment and treatment delays may result in poorer patient outcomes. Moreover, ischemic stroke patients have a high rate of mortality and morbidity. In addition, the undiagnosed, unreported cases and the unawareness about the disease may also impact the acute ischemic stroke market growth.
Report Metrics
Details
Study Period
2019–2032
Coverage
7MM [the United States, the EU-4 (Italy, Spain, France, and Germany), the United Kingdom, and Japan]
Base Year
2019
Acute Ischemic Stroke Market CAGR
10.6 %
Acute Ischemic Stroke Market Size in 2022
USD 1.3 Billion
Key Acute Ischemic Stroke Companies
Acticor Biotech, DiaMedica Therapeutics, Lumosa Therapeutics, Bristol Myers Squibb, Janssen Pharmaceutical, Genentech, Inc., Athersy, Healios K.K., NoNO Inc., Bayer, ZZ Biotech, Biogen Inc., Revalesio Corporation, AbbVie, TrueBinding, Inc, Silver Creek Pharmaceuticals, and others
Key Pipeline Acute Ischemic Stroke Therapies
Glenzocimab (ACT017), DM199, LT3001, Milvexian, Tenecteplase, Invimestrocel (HLCM051), Nerinetide, Asundexian (BAY2433334), 3K3A-APC, BIIB131 (TMS-007), BIIB093 (IV Glibenclamide; CIRARA), RNS60, Elezanumab (ABT-555), TB006, Scp776, and others
Scope of the Acute Ischemic Stroke Market Report
Discover more about acute ischemic stroke drugs in development @ Acute Ischemic Stroke Clinical Trials
Table of Contents
1.
Acute Ischemic Stroke Market Key Insights
2.
Epidemiology and Market Methodology
3.
Acute Ischemic Stroke Market Report Introduction
4.
Acute Ischemic Stroke Market Overview at a Glance
5.
Acute Ischemic Stroke Market Executive Summary
6.
Disease Background and Overview
7.
Acute Ischemic Stroke Treatment and Management
8.
Acute Ischemic Stroke Epidemiology and Patient Population
9.
Patient Journey
10.
Acute Ischemic Stroke Marketed Drugs
11.
Acute Ischemic Stroke Emerging Drugs
12.
7MM Acute Ischemic Stroke Market Analysis
13.
SWOT Analysis
14.
KOL Views
15.
Unmet Needs
16.
Market Access and Reimbursement
17.
Appendix
18.
DelveInsight Capabilities
19.
Disclaimer
Related Reports
Acute Ischemic Stroke Epidemiology Forecast
Acute Ischemic Stroke Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted acute ischemic stroke epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
Acute Ischemic Stroke Pipeline
Acute Ischemic Stroke Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key acute ischemic stroke companies, including Genentech, Acticor Biotech, DiaMedica Therapeutics, and NoNO, among others.
Ischemic Stroke Market
Ischemic Stroke Market Insight, Epidemiology, and Market Forecast – 2032 report delivers an in-depth understanding of the market trends, market drivers, market barriers, and key ischemic stroke companies, including Bristol Myers Squibb Company, Ltd., ZZ Biotech, Biogen, and Bayer, among others.
Ischemic Stroke Epidemiology
Ischemic Stroke Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical, and forecasted ischemic stroke epidemiology in the 7MM.
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SOURCE DelveInsight Business Research, LLP
DelveInsight Business Research, LLP